Hi Arthur. Wanted to say hello to a fellow CMLer. Are you on a TKI? Where is U of M? If you are able to, I would consult with a CML specialist (hematologist/oncologist) and ask him/her all the questions you need answers to. Knowledge is power. IF I can help you with anything, please let me know. I'm nearing 9 years with CML. Take care, Susan (Blood-Cancer.com Team Member)